Pneumococcus is the most common cause of community acquired pneumonia(CAP) accounting for 19-25% of all cases. The incidence of cAp increases with age and so does the morbidity and mortality. hospitalization rates for cAp in the elderly (>65 years) have been reported to range from 31-78%. The increase in the elderly population globally and in singapore makes intervention in reducing pneumococcal disease an important priority. At this time, pneumococcal disease is potentially the leading cause of vaccine preventable disease in man. Researchers focused on the improving the immunogenicity by using a protein conjugate to prime the immune system and to induce longer lasting memory.