The number of persons with disabilities (PWD) that GPs will attend to will increase due to the rapid ageing population and increasing life expectancy in Singapore. It is important for GPs to work in partnership with family caregivers in order to optimise the healthcare of all PWD, including those with congenital and acquired disabilities. This paper examines the challenges and needs of caregivers; and suggests ways for GPs, caregivers and government to enhance the healthcare experience of PWD.