Depressive disorder affects the quality of life, increases the economic burden from cost of treatment or loss of employment, and may lead to suicidal tendency. Depressive disorder is the commonest psychiatric problem in primary care practice. However, it is often undetected and the under-diagnosis is partly because the depressed person is preoccupied with physical complaints of pain or aches, this could mislead the attending doctor. The early symptoms of depressive disorder are low mood, loss of energy, anhedonia, poor sleep, poor appetite and loss of interest in work or activities (Table 1). These symptoms will be present daily and may affect quality of life